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This product needs to be refrigerated!

Koi Zyme is a biological formula of naturally occurring bacteria, enzymes and micro nutrients. It contains no chemicals, no medications and no antibiotics of any kind.

KoiZyme will not kill the bacteria that has already infected your fish but it will allow quicker healing and reduce the chance of a secondary infection occuring by keeping the bad bacteria out of the water.

When used as directed, it reduces the threat caused by Aeromonas, Pseudomonas and other pathogenic bacteria. In reality it is impossible to remove 100% of Aeromonas and Paseudomonas bacteria from the pond water. The levels of Aeromonas and Paseudomonas will be low enough that your Koi will not become infected when they scrape their slime coat or become stressed.

ONLY Koi Zyme has Micro Nutrients. This provides a food source for the good bacteria that keeps them active until used in your pond.

32oz Koi Zyme

~Price $48.00 32oz treats 48,000 to 96,000 gallons.

16oz Koi Zyme

Price $25.00 1 Pint 16oz Treats 24,000 to 48,000 gallons.

For the Koi Care KennelProduct Compatibility Chart Click Here.

This page will also show the minimum water temperature for the products and which products can be used if you have salt in your pond.

Koi fish pictures

When a Koi gets a wound, the “bad” bacteria consume the dead cells around the wound. They do not eat healthy cells... only the dead cells. The problem is the bacteria emit as a waste product—a toxin—that kills whatever cell it comes in contact with. Therefore, as it eats a dead cell, its toxin kills the next cell so it has more food and can reproduce and on and on.

Koi Zyme is a relatively new product that is bacterial in nature. It is safe to handle, not caustic, does not cause undue stress, and impossible to overdose. It is simply a bottle of safe bacteria.

It also eats the dead cells but give off a waste product that is not toxic and does not kill the next cell in line. These “good” bacteria compete with the bad bacteria. They do such a good job of it, the bad bacteria simply starve to death.

Koi Zyme - the pro-biotic that effectively prevents Ulcer Disease.

When it is introduced into pond water that is infected with Aeromonas, Pseudomonas or any gram negative or gram positive bacteria, the bacteria and enzymes in Koi Zyme competes with these pathogens for the nutrients in the pond water. These nutrients are primarily a nitrogen based nutrient from fish waste. It will consume these nutrients and thus starve Aeromonas and Psuedomonas. The bacteria counts (CFU's) of these pathogens will then be reduced to such a low level that they will not have an affect on your fish.

There are a number of tricks for protecting Koi such as feeding them immune system enhancing food, but the one that seems to work the best is the use of Koi zyme.

What would you give to have a totally natural non chemical organic method of reducing the levels of pathogenic bacteria in your system with ZERO negative impact on Koi or the vital life giving nitrifying bacteria in your filter?

For more Koi Care Kennel Products Click Here

Quart 32oz treats 48,000 to 96,000 gallons. Five initial treatments are required and then one a week maintenance treatments will keep your pond healthy.

It should be used when pond water temps reach 52° F and above.

Koi Zyme will NOT harm the biofilter and can be used with any percentage of salt.

Shelf life: 8 to 10 months at room temps and 20 months if kept refrigerated.

32oz Koi Zyme

~Price $48.00 A Quart 32oz treats 48,000 to 96,000 gallons.

16oz Koi Zyme

Price $25.00 1 Pint 16oz Treats 24,000 to 48,000 gallons.

When used as directed, it will reduce the bacterial count of Aeromonas, Pseudomonas and other pathnogenetic bacteria to such low levels that they will not be a threat to the health of your fish.

It is impossible to completely remove the Aeromonas and Pseudomonas bacteria from the pond water, but KoiZyme, when used on a regular weekly basis, will keep the Aeromonas, Pseudomonas and other pathogens levels so low, they will not affect the fish.

For More Information On How Koi zyme Works Click Here

Below is an excerpt from a post Richard E. Carlson made on the AKCA web board. The question was related to the use of Lymnozyme (KoiZyme) on fish already infected with an aeromonas bacteria infection:

First, every pond has aeromonas bacteria.. it is a fact of life. They typically only become a problem when the fish are stressed or weakened by something else. Consider them opportunistic, if you will, as they are looking for open wounds caused by injury or parasites, flukes, etc. Lymnozyme reduces the number of aeromonas bacteria by exclusion, in that it competes with the food source of the aeromonas, which is an element of the fish's feces.

Lymnozyme (Koi Zyme) stays in effect for about four days in your pond, so you can see that its addition reduces the aeromonas count quickly. The most opportune time to use it is when you suspect that your fish are stressed by bad water, parasites, flukes, etc. and susceptible to infection.

Lymnozyme is effective down to about 45° F.

Koi fish pictures

Questions and Answers

Q: Can I use my U.V. Light when treating?
A: You should turn off your U.V. Light when treating with Koi Zyme for the first five initial treatments only. It is OK to turn the U.V. Light back on for the rest of the season once you get into the "Maintenance" treatment of 1/2 the label dosage.

Q: How long do I treat?
A: You start treating in the Springtime once the water temp reaches 50° to 52° F. If you had treated with KoiZyme the previous year you would still "start over" and do the five initial treatments at full dosage rate, then go into the "Maintenance" program. You should continue the "Maintenance" program the entire season until the water temp drops back into the low 50° F area.

Q: I have heard that water temperature affects the dosage rate. Is that true?
A: Yes. Water temp does have an affect on the dosage rate. This is because the KoiZyme bacteria is not as active (or hungry) at the lower water temps. Here is the dosage rates for the various water temps:
  • 50° F to 62° F -- Double the label dosage of 20ml (4tsp) to 40ml (8 tsp).
  • 63° F to 68° F -- 1.5 X the label dosage of 20ml (4tsp) to 30ml (6 tsp).
  • 69° F and above -- Normal label dosage
Q: Can I use salt when treating with KoiZyme?
A: Yes. It works equally well in fresh or salt water.

Q: Can I use while treating with other pond products?
A: KoiZyme can be used while treating your pond with most other products. Other "probiotics" such as Micro-Lift are OK to use at the same time. This is because no other "probiotic" (bacterial based product) consumes the same "nutrients" as KoiZyme, therefore they do not compete with each other.

If you are going to treat your pond with a chemical product such as a parasite product, wait until you have completed the first 5 initial treatment of KoiZyme. Most chemical based products will kill the KoiZyme bacteria, but once you are into the "maintenance program" of Koi zyme, thats OK. This is due to the fact that Koi Zyme only lives in your pond for 3 to 4 days (it has gone through it's complete life cycle at that point). And in the "maintenance program" you are simply keeping the bad "nutrient" level down so that Aeromonas does not return.

If you kill the Koi Zyme bacteria one week during the "maintenance program" the bad "nutrients" will not build back up that quickly. Simply continue on with the "maintenance program" after treating with your chemical product. Some other products that should not be used during the "initial dosage" treatment of Koi Zyme are Amquel, and liquid antibiotics.

Q: I currently have a Aeromonas problem, should I increase the Koi Zyme dosage and is that safe to do?
A: We strongly recommend that you double the dosage rate if you have a existing Aeromonas problem. By doubling the dosage rate, you will speed up the rate that it will consume the bad "nutrients" from the pond water, thus starving out the Aeromonas sooner.

It is almost impossible to overdose with KoiZyme. I have dosed my hospital tank, with 9 Koi in it, at the rate of 200ml (over 6 oz.)/1,000 gallons for a period of three weeks with no affect on the fish or the biofilter. Also, by increasing the dosage rate during an existing Aeromonas problem, Koi Zyme bacteria will displace the Aeromonas bacteria off the ulcer or infected area of the fish.

You will see the infected area start to "white over" soon after treatment is started. BUT, let me say this, if the ulcer is in an advanced state (into the "meat" of the fish), you should treat that fish with antibiotics because most likely that Aeromonas bacteria has gotten into it's bloodstream.

Q: Does the label dosage of 20ml (4tsp) work for all ponds?
A: No, not all ponds. We have found that by far most ponds respond very well to the label dosage of 20ml (4tsp)/1,000 gallons. Every pond has its own "biological personality" and therefore the bad "nutrient" level in that pond can vary.

We have found that about 85% to 90% of ponds tested responded well to the label dosage rate. If the pond is heavily stocked, or poorly physically filtered (the handling of the fish waste), then the bad "nutrient" level (nutrients given off the fish waste) will be higher in that pond and therefore more Koi zyme will be required to lower those bad "nutrient" levels.

The worst pond we have tested had an Aeromonas count of 500,000 CFU (Colony Forming Unit). This is an extremely high count and indicates that there was excessive amounts of bad "nutrients" in that pond, allowing the Aeromonas count to get to 500,000 CFU. That pond, when treated at the rate of 60ml/1,000 gallons (triple the label dosage), responded well, dropping the Aeromonas count to 18,000 CFU within 3 weeks. That pond DID NOT respond to the label dosage of 20ml/1,000 gallons.

Q: Does Koi Zyme have any affect on my biofilter?
A: No, not at all. The Koi Zyme bacteria's do not consume ammonia or nitrites, therefore they do not compete with your filter.

For the Koi Care KennelProduct Compatibility Chart Click Here.

This page will also show the minimum water temperature for the products and which products can be used if you have salt in your pond.

You are here: Home > Pond Shop > Fish Medicine for Sick Fish > Koi Zyme


As a Koi pond owner I have experienced such joy as well as extreme sadness. Over the last 10 years it has been so peaceful and wonderful to sit by my pond admiring my beautiful Koi. However, intermittently I have been brought to tears when disease or predators have killed my fish. A couple of years ago I quit naming my koi because it seemed much harder to loose a named pet than one without a name. I had done what I could to discourage and protect my fish from the blue heron, raccoons, fox and snapping turtles. However I still had intermittent problems with microorganisms, attacking and killing my fish. Last summer it broke my heart when I lost a large number of koi to some type of disease, I am still not sure what it was - bacteria or flukes etc??? I treated our pond with medications and then started KoiZyme in an attempt to make our fish more resistant and prevent future disease. Since that time, my fish have never seemed so “happy and healthy”!!!! So far KoiZyme has worked as advertised, which thrills me! I am hoping that I will never have to treat my fish again for bacterial or parasitic diseases. I am feeling comfortable enough with KoiZyme that I think I may take a chance and start giving my Koi names again!!!! A.S.

Thanks for the prompt delivery!

We are all set to resume KoiZyming! I will gladly do business with you again in the future.

Pamme from CA

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