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Koi Herpes Virus and Spring Viraemia Carp (SVC)


There are two known viruses of importance to Koi. They can quickly kill the fish and are both highly contagious.

  • Koi Herpes Virus (KHV)
  • Spring Viremia of Carp (SVC) (Rhabdovirus carpio)

KHV Disease was first recorded in Israel in 1998 following large-scale mortalities in farmed fish. Further losses attributed to the virus were later found in Europe and the USA and have subsequently been reported throughout the world including Japan, Malaysia and South Africa. The virus was first identified in the UK in 2000 and has subsequently proven to be widely distributed in ornamental dealers and hobbyists fish stocks.

Other cyprinids such as common goldfish seem to be immune to the disease but can become asymptomatically infected with the virus and therefore may become carriers.






As of January 2007, KHV was added to the World Organization for Animal Health (OIE) notifiable disease list for fish. Because of this listing the United States Department of Agriculture Animal and Plant Health Inspection Service (USDA APHIS) asks that accredited veterinarians and diagnostic laboratories report positive cases of KHV to the area veterinarian-in-charge (AVIC) of the state where the fish originated. However, no client information (e.g., name, address) will be requested.

This information will help USDA determine what the prevalence of KHV is in the United States. USDA APHIS has no health requirements specific for KHV for Koi or other fish moving interstate or internationally. There is no mandatory depopulation for populations of Koi infected with KHV. It is up to the owner of those animals to decide what course to take.


The symptoms of Koi Herpes Virus are:


  • Fatigue
  • Pale Patches of Skin
  • Internal Organs become damaged

Investigation of koi herpesvirus latency (or dormant state) in Koi.

Koi herpesvirus (KHV) has recently been classified as a member of the family of Alloherpesviridae within the order of Herpesvirales. One of the unique features of Herpesviridae is dormant infection following a primary infection. However, KHV latency has not been recognized. To determine if latency occurs in clinically normal fish from facilities with a history of KHV infection or exposure, the presence of the KHV genome was investigated in healthy koi by PCR and Southern blotting. KHV DNA, but not infectious virus or mRNAs from lytic infection, was detected in white blood cells from investigated koi. Virus shedding was examined via tissue culture and reverse transcription-PCR (RT-PCR) testing of gill mucus and feces from six koi every other day for 1 month. No infectious virus or KHV DNA was detected in fecal secretion or gill swabs, suggesting that neither acute nor persistent infection was present. To determine if KHV while dormant can be reactivated, six koi were subjected to a temperature stress regime. KHV DNA and infectious virus were detected in both gill and fecal swabs by day 8 following temperature stress. KHV DNA was also detectable in brain, spleen, gills, heart, eye, intestine, kidney, liver, and pancreas in euthanized koi 1 month post-temperature stress. Our study suggests that KHV may become latent in white blood cells and other tissues, that it can be reactivated from latency by temperature stress, and that it may be more widespread in the koi population than previously suspected.

Refrences:Eide KE, Miller-Morgan T, Heidel JR, Kent ML, Bildfell RJ, Lapatra S, Watson G, Jin L.

Source: Department of Biomedical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis, OR 97331, USA.

J Virol. 2011 May;85(10):4954-62. Epub 2011 Mar 9.



For more Behavior Symptoms of KHV, Prevention of KHV, Pictures of KHV and, what you should do if KHV is Positively Identified, Click Here for the All About Koi Ebook.




SVC Spring Viraemia Carp (Rhabdovirus carpio)


This is a disease which you really hope you will never experience as it is a notifiable condition. This means that once it is identified, you must inform the relevant authorities who may well take the step of killing your stocks and disinfecting your whole system. SVC should not be a concern for Koi keepers as long as they do not introduce stocks from the wild, especially if they live in a country where SVC is present. In fact it is illegal in most instances to take and move wild stocks without first discussing your intentions with the appropriate authorities.

It is also wise to avoid importing Koi from a region or country which is known to have SVC. That is why strict licensing is in place in countries where SVC is not currently a problem.

SVC will cause symptoms of ulceration on the skin of your Koi, as well as areas of reddening as the virus progresses. Sometimes these are accompanied by swelling of the belly area, and a loss of color in the gills. Surprisingly SVC will not result in heavy loses of adult Koi, but if you have young or small Koi and they are infected, losses of 100% may be expected.

If you are unfortunate enough to encounter this disease in your fish, it is vital that the correct authorities are notified. In most cases the laboratory carrying out the testing will do this as a matter of course. Although the subsequent culling may be hard to handle, try to remember that it is not only in your best interests but also those of the whole Koi industry.

Fish will usually survive SVC; but their carrier state is unconfirmed.


References: Manual of Koi Health by: Keith Holmes and Tony Pitham


Mortality is usually high. Unlike KHV, which seems to affect only koi and carp, this disease affects goldfish and other Cyprinids, including wild populations and bait fish. The USDA is exploring method(s) of controlling the spread of SVC in this country including quarantine, health certificates, importation guidelines, vaccinations, testing programs etc. Official guidelines should be available soon.

To find a Fish Vet in your Area


Click Here to Learn About Other Fish or Koi Diseases Click Here for Koi Health Ailments Click Here to for the Koi Health and Wellness Center






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SVC kills 5-10% of the population of affected fish and seems endemic. KHV kills 90% of affected fish if untreated and is rare.




PCR Tests

PCR, or polymerase chain reaction, which is used to confirm the presence of both KHV and SVC is an analytical technique that is widely used in genetic fingerprinting. In the test, an identifiable part of the DNA of an organism or viral particle is amplified using the DNA's replication process. The PCR test is extremely sensitive, so very little material is needed for positive identification. Samples should be fixed in 75 percent ethanol and stored in a freezer until they can be sent on to a laboratory that specializes in these tests. Lately, improved analytical techniques allow dry swabs of gill tissue to be used for viral detection. Your local Koi club will be able to advise on where PCR tests can be done.




June 11, 2008 Koi Herpes Virus Outbreak

It has been reported that Sakai Hiroshima Fish Farm, Hiroshima Prefecture (roughly 1,200km away from Niigata), have had an occurrence of KHV at the farm.

We understand that the incident, isolated to one of the farms mud ponds, has been reported to the relevant authorities who are carrying out testing.




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